Blue Review
A Provider Publication

April 2018

BCBSOK Approves Coverage of New Shingles Vaccine Shingrix

Blue Cross and Blue Shield of Oklahoma (BCBSOK) now covers Shingrix, a new two-dose vaccine approved by the Food and Drug Administration (FDA) in October 2017 for reducing shingles and related nerve pain. Until recently, the only vaccine available for shingles was Zostavax which is 51 percent effective. Clinical trials show Shingrix is 91 percent effective.

For immunocompetent adults ages 50 and older, the Advisory Committee on Immunization Practices (ACIP) recommends Shingrix over Zostavax. They also recommend that immunocompetent adults who have already had Zostavax also get Shingrix.

BCBSOK covers two doses of Shingrix administered to patients ages 50 and older, even if they have already received Zostavax based on current ACIP recommendations. It is important to check eligibility and benefits information to confirm details regarding copays, coinsurance and deductibles before administering this vaccine to BCBSOK members. 

Vaccine Shingrix Zostavax
Dosage schedule Two doses (2nd dose 2-6 months later) One dose
Vaccine description Recombinant, adjuvanted Live-attenuated
FDA recommended age Adults 50 and older even if previously vaccinated with Zostavax Adults 50 and older
Overall efficacy by year 3* 91% 51%
Administration site Intramuscular Subcutaneous
CPT® Code 90750 - Zoster (shingles) vaccine, (HZV), recombinant, sub-unit, adjuvanted, for intramuscular injection 90736 - Zoster (shingles) vaccine (HZV), live, for subcutaneous injection

*Zostavax and Shingrix prescribing information

For more information on Shingrix, see the Center for Disease Control and Prevention’s Jan. 26, 2018, edition of Morbidity and Mortality Weekly Report. Click here for the FDA-approved prescribing information for Shingrix. For more information on patient coverage, contact your BCBSOK representative.

Details on our complete, approved immunization schedule can be found on the BCBSOK Provider page under Standards & Requirements, Clinical Payment and Coding Policies, “Preventive Services Policy CPCP006”.